Kuru is an untreatable vampiric disease that often afflicts Nosferatu vampires, but is not limited to their number. Kuru affects muscle coordination, bouts of psychological instability (including paranoia and schizophrenia) and spontaneous, manic laughter. Kuru develops when a vampire consumes large amounts of either vampiric or human flesh, along with the blood.

While Kuru is rare among normal vampires, it is rife among the Nosferatu population, due to the relatively high number of Donor cannibalization (which is caused by Nosferatu's insatiable Blood Lust).

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